Roche — Jobs & Company Profile

Global Head Regulatory Data, Digital and AI

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.The PositionThe PTR Data, Digital and AI team drives the technological transformation of our regulatory domain to accelerate the delivery of novel therapeutics to patients worldwide. By leveraging cutting-edge automation, data analytics, and artificial intelligence, we streamline regulatory submissions and processes and empower our global network to operate with agility and precision.The OpportunityLead the definition, ownership, and execution of the digital, automation, and AI strategy across Technical Regulatory.Translate strategic visions into actionable tactical execution plans with defined milestones, clear ownership, and measurable business impact.Evaluate, architect, and deploy innovative digital solutions, including generative AI, machine learning, and routine workflow automation.Establish robust data governance and AI governance frameworks to ensure compliant, high-quality data stewardship across the ecosystem.Partner with IT, RIM Business Owners, Data Stewards, and technology vendors to drive end-to-end delivery of digital capabilities.Build advanced analytics, business intelligence, and real-time performance dashboards to track organizational effectiveness.Champion change-management plans, process optimization, and training curricula to ensure broad adoption of new digital tools.Represent department needs in senior leadership and governance forums while actively engaging with external industry networks and regulatory bodies.Lead, mentor, and empower a high-performing team of strategic digital leads while managing portfolio priorities and resource allocation.Who You AreYou are an inspiring, forward-thinking leader who thrives at the intersection of enterprise data governance, AI implementation, and digital innovation. You empower high-performing, self-managed teams through visionary coaching, open communication, and an agile mindset, while effortlessly connecting strategy with execution to drive organizational transformation.Furthermore, you possess the following qualifications and experience:University degree (Master's or PhD preferred) in Data Science, Computer Science, Engineering, Life Sciences, or a related technical discipline.Extensive experience in the pharmaceutical or biotechnology industry with a strong focus on digital transformation, technology implementation, and advanced analytics. A good understanding of regulatory affairs would also be beneficial.Deep expertise in enterprise data governance, AI governance, master data management, and building business intelligence platforms.Proven background in establishing cross-functional change management, senior stakeholder alignment, and leading end-to-end operational improvements.Leadership experience in coaching, mentoring, and developing high-performing teams in an agile setting.Experience in pharmaceutical regulatory affairs operations is a distinct advantage.Are you ready to pioneer cutting-edge solutions that accelerate breakthroughs for our patients? We are looking forward to your application – join us now and become part of our journey! Where pay transparency applies, details are provided based on the primary posting location. For this role, the primary location is Basel. If you are interested in additional locations where the role may be available, we will provide the relevant compensation details later in the hiring process.Who we areA healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.Let’s build a healthier future, together.Roche is an Equal Opportunity Employer.

Basel

Development Engineer (contract 80-100%)

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.The PositionIn a global, cross-functional environment, the System Development (SD) department within R&D is responsible for workflow optimization and successfully integrating hardware, software, consumables, and reagents to perform the system verification of diagnostics instruments. As a Development Engineer, you will work as a cross-functional team on automating and tooling to maintain and further develop launched complex diagnostic systems.In this position, you will be responsible for the following areas:Elaborating on (Cobots-)Robotics concepts within a laboratory environment towards our vision of a dark lab by fully automating laboratory operations and workflows. Programming, testing, and maintaining of newly created and existing automated solutions within our laboratories.Supporting our Integration Teams in the installation and troubleshooting of Robotics Solutions within our laboratory environmentPlan, coordinate, and execute work packages within your area of responsibility, including reporting and escalating topics or issues to the team and management.Be able to work as an individual and as part of a team.Who you are:You are graduated with a bachelor's or master preferably in computer science, with specific knowledge in, e.g., robotics and/or vision, electrical engineering, mechanical engineering or systems engineering or equivalent.Knowledge of professional Software development with one or more programming languages (e.g. UR-Polyscope, Python, C#/NET, LabView)You are excited to work as a professional in the medical diagnostics industry.Excellent spoken and written command of English (German is advantageous).You can communicate appropriately with different target groups.You are motivated to build, manage, and foster relationships and networks within the department and the related projects.Quick grasp and understanding of complex issues conceptual and creative thinking.Please note that this vacancy is not currently linked to an open position. We are anticipating future needs in our organization. If you are interested in this kind of role, please apply today, and we may contact you should a position matching your profile become available.Who we areA healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.Let’s build a healthier future, together.Roche is an Equal Opportunity Employer.

Rotkreuz

Software Tester within RMD System Development (contract)

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.The PositionThe Position(Please note that this vacancy is currently not linked to an open position. We are anticipating future needs in our organization. If you are interested in this kind of role, please apply today and we may contact you should a position matching your profile become available.)In a global and cross-functional environment, the System Development department is responsible for workflow optimization and the successful integration of hardware, software, consumables, and reagents to finally perform the system verification of diagnostics instruments.As a System Development Software Tester, you will work as a part of a cross-functional team on the development of new complex diagnostics systems consisting of fluidics, robotics software, thermal, electrical, mechanical, and biochemistry elements.As a Software Testergineer in the new Analyzer Project, your main responsibilities will consist of (but will not be limited to):Plan and execution of the work packages within the area of responsibility, including reporting and escalation of issues to the management.Experienced with Windows and Linux Operations SystemKnow-how in setting up an automated testing environment and familiar in using data analysis tools to provide statistical data to the managementExperienced in using Network Protocols (TCP/IP, HTTP, and SSL)Familiar in using Gateways, Firewalls and using Remote AccessSubject matter expert for Communications protocols between instruments and Laboratory informations systems(LIS). Provide guidance and support to others. Flexibility to transfer knowledge to different tasks/subprojects within SD.Experimental design and execution of the experiments in the lab. Creation of Test Cases based on Product Requirements. Execution of Test Cases, analysis of the results, and creation of the respective regulatory documents. Issue tracking and verification of bug fixes/Anomalies.Generate required documentation/procedures/technical reports in support of daily activities and be able to author official documents in English (e.g., Design history Files) for the preparation of milestones. Prepare and deliver presentations of project results to own or other groups.Coordinate efforts with other functional areas to accomplish tasks: Hardware-, Software-, Consumables-, Assay-and Algorithm-Development.Who you areYou’re someone who wants to influence your development. You’re looking for a company where you have the opportunity to pursue your interests across functions and geographies. Where a job title is not considered the final definition of who you are, but the starting point.To be successful in this role (you provide):Degree in a technical or life sciences discipline (e.g., Software- or Electrical Engineering,Electronic/Automation, Bio- and Process-Engineering,) or related job experience.Minimum 1 years of work experience in the development of diagnostic systems in a System Development or related fieldAbility to work independently, handling cross-departmental development tasksExcellent communication skills and fluency in English and GermanStrong analytical and interdisciplinary thinkingExperience in statistical data analysisExperience in and willingness to work in a highly regulated industry and labs with biosafety levels S1and S2Who we areA healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.Let’s build a healthier future, together.Roche is an Equal Opportunity Employer.

Rotkreuz

Development Engineer (contract)

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.The Position In a global, cross-functional environment, the System Development (SD) department is responsible for workflow optimization and successfully integrating hardware, software, consumables, and reagents to perform the system verification of diagnostics instruments.As a Development Engineer, you will work as a part of a cross-functional team, working on Nucleic Acid Purification, PCR and Sequencing, on developing complex diagnostics systems. You will perform hands-on experiments, Hardware (HW) and Software (SW) testing, including evaluation of system performance, error handling, and reliability improvements.Please note that this vacancy is not currently linked to an open position. We are anticipating future needs in our organization. If you are interested in this kind of role, please apply today, and we may contact you should a position matching your profile become available.In this position, you will be responsible for the following areas:Plan and execute the work packages within the area of responsibility, including reporting and escalating issues to management.Subject matter expert for an assigned area of responsibility. Provide guidance and support to team members.Generate required documentation/procedures/technical reports. Prepare and deliver presentations of project results to team and management.Experimental design and execution of the experiments in the biosafety levels S1 and S2 laboratory. Creation of Test Cases based on Product Requirements. Execution of Test Cases, analysis of the results, and creation of the respective regulatory documents. Issue tracking and verification of bug fixes/Anomalies.Troubleshoot, debug, and upgrade existing systems. Document and maintain software functionality.Coordinate efforts with other functional areas to accomplish tasks: Hardware, Software-, Consumables-and Assay-Development.Who you areYou are someone who wants to influence your development. You are looking for a company where you have the opportunity to pursue your interests across functions and geographies. A job title is not considered the final definition of who you are but the starting point.The ideal candidate for our dynamic, international team will have the following skills and experience:Degree in a relevant life science discipline (e.g. (e.g. biology, biotechnology, biomedical informatics, engineering related to life sciences) or corresponding job experienceInterest in resolving technical problems and interdisciplinary teamworkExperience and willingness to work in a highly regulated industry and labs with biosafety levels S1 and S2.Familiarity with or strong interest in software and engineering applications and tools .Enthusiastic team player with good communication and collaboration skills. Solution-oriented, autonomous, and proactive working style.Proven experience in laboratory diagnostics and/or service & support, as well as supporting HW and SW, are additional assets.Working knowledge of English (written and spoken), and German a strong asset Who we areA healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.Let’s build a healthier future, together.Roche is an Equal Opportunity Employer.

Rotkreuz

Machine Learning Scientist - Quantum Chemistry

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.The PositionJoin the small-molecule team within AI for Drug Discovery (AI4DD), formerly Prescient Design, at Roche and Genentech’s Computational Sciences Center of Excellence as a Machine Learning Scientist / Senior Machine Learning Scientist in Quantum Chemistry. You will combine machine learning methods and quantum chemistry to build fast, accurate models that power small-molecule drug discovery. You will work with world-class computational and experimental scientists and leverage proprietary datasets and state-of-the-art compute.The OpportunityCreate cutting-edge solutions that combine quantum chemistry and machine learning algorithm development to model small-molecule energetics and protein–ligand interactions, from conformation and reactivity to binding affinity and free energy.Build synthetic datasets using quantum mechanics and related methods to shape novel research directions in ML.Develop deployable pipelines that are robust, scalable and reproducible, and feed directly into molecular-design tools used across Roche.Drive scientific impact through publications, open-source releases, and talks at internal and external conferences.Collaborate widely with world-class computational and experimental researchers at Roche and with academic partners.Who you areYou bring deep machine-learning expertise with a strong theoretical foundation in linear algebra, probability and optimization, and you build models from first principles.You have hands-on quantum chemistry experience and fluency in toolkits such as Psi4, PySCF and ORCA, as well as semi-empirical methods like xTB.You are fluent in Python and modern ML frameworks such as PyTorch or JAX.You hold a PhD or equivalent research depth in machine learning, computational chemistry, chemical engineering or a related quantitative field such as physics or statistics.You have a record of scientific excellence evidenced by journal and conference publications or a public portfolio of relevant projects (e.g. hosted on GitHub/GitLab).PreferredExperience in scientific software development, scaling ML training, and applying models to drug discovery. Experience generating large-scale synthetic datasets.Location & Travel RequirementsThis position must be based in either Welwyn Garden City in the United Kingdom (preferred) or Basel, Switzerland. Although this can be a hybrid role, there is an expectation of ongoing and sustained site presence, in compliance with local company site requirements.If building physics-grounded machine learning models that bring better medicines to patients faster is your calling, apply now and help shape the future of small-molecule drug discovery.#ComputationCoE#tech4lifeComputationalScience#tech4lifeAI Where pay transparency applies, details are provided based on the primary posting location. For this role, the primary location is Welwyn. If you are interested in additional locations where the role may be available, we will provide the relevant compensation details later in the hiring process.Who we areA healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.Let’s build a healthier future, together.The statements herein are intended to describe the general nature and level of work being performed by employees, and are not to be construed as an exhaustive list of responsibilities, duties, and skills required of personnel so classified. Furthermore, they do not establish a contract for employment and are subject to change at the discretion of Roche Products Ltd. At Roche Products we believe diversity drives innovation and we are committed to building a diverse and flexible working environment. All qualified applicants will receive consideration for employment without regard to race, religion or belief, sex, gender reassignment, sexual orientation, marriage and civil partnership, pregnancy and maternity, disability or age. We recognise the importance of flexible working and will review all applicants’ requests with care. At Roche difference is valued and we are proud to be an equal opportunity employer where you are encouraged to bring your whole self to work.

Basel

Software Senior Technical Lead Rust (80-100%)

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.The PositionIn a global, cross-functional environment, the PCR Software Development chapter develops, delivers and and maintains integrated, unified and reliable software solutions for Molecular Diagnostics Systems by leveraging our advanced capabilities, in-depth knowledge and strong internal & external partnerships driving the accuracy, efficiency and agility in innovating the Molecular Lab experience for our customers and patients throughout their journey.The OpportunityAs a Software TechLead, you will be part of a cross-functional team playing a pivotal role in facilitating agile processes and ensuring effective collaboration in developing software solutions. You will enable our Molecular Lab network to deliver accurate and timely diagnostic solutions and your contributions will support the Diagnostics 10-year ambition.In this position, you will be challenged in the following areas:You work with cross-functional teams and stakeholders (Product Owner, System Architect, Solution Architect, System Engineers, etc.) to understand and translate complex business and customer needs into effective technical solutions and communicate these to the team and the stakeholders.You design and develop innovative software solutions that meet regulatory requirements as well as fulfill system quality attributes like scalability, performance, reliability, maintainability, interoperability, extensibility, etc.You guide the team to adhere to best practices in software development, including code reviews, testing, and continuous integration, to deliver high-quality solutions and foster a culture of continuous improvement and technical excellence.You act as a mentor and role model, guiding and empowering team members in technical development, promoting a collaborative working environment and contributing effectively to the team's success.Who you areYou as a candidate for our dynamic team will have the following skills and experience:Bachelor’s degree or equivalent practical experience in the specialized field of Software Development / Engineering and experience in IVD software development is a plus for succeeding in the roleSeveral years of proven experience in software development, with a demonstrated passion and hands-on professional experienceExperience working with Rust incl. a solid understanding of Rust's core concepts (ownership, borrowing, and lifetimes), experience with asynchronous programming in Rust (e.g., using async/await) and familiarity with common Rust libraries and frameworks (e.g., tokio, actix-web, rocket, serde, sqlx) is a plus. If no prior Rust experience is available, willingness to learn and develop later on in Rust is required and experience in a familiar language (like C++) is preferred.Experience with modern system architectures like event-driven architecture and DDD, quality-driven practices such as TDD and BDD, or containerization technologies like Kubernetes is a plus.Demonstrated experience in transforming customer value into implementable solutions.Capable of solving complex issues creatively and effectively, using a multi-faceted approach based on thorough analysis to resolve complex project challenges.Excellent communication skills with the ability to foster an inclusive and diverse environment as well as collaborate effectively within and across teams.Leads by example to foster cross-functional value delivery and to establish a psychologically safe working environment and empowers its own team and holds people accountable by creating conditions for ownership.Motivation to make an impact to your fellow team members, our company, our customers and our patients.Certified ISAQB or equivalent is a plus.Every role at Roche plays a part in making a difference in patients’ lives. Apply now and join us in making an impact! Please submit a CV to complete your application. Who we areA healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.Let’s build a healthier future, together.Roche is an Equal Opportunity Employer.

Rotkreuz

Lehrstelle als Informatiker:in EFZ Applikationsentwicklung (ab August 2027)

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.The PositionWichtig: Nach deiner Bewerbung melden wir uns innerhalb weniger Tage per E-Mail bei dir. Um sicherzustellen, dass du keine wichtige Nachricht verpasst, bitten wir dich, neben deinem Posteingang auch den Spam- oder Junk-Ordner zu prüfen. Falls du innerhalb einer Woche nichts von uns hörst, melde dich unter basel.berufslehre@roche.com.Weisst Du bereits, was du nach deinem Abschluss machen wirst? Weltverbesserer oder Lebensretterin werden? Nicht nur Du musst Deine Zukunft neu erfinden. Auch wir. Wir bei Roche arbeiten mit einem Ziel - innovative Tests und Medikamente zu entwickeln und Daten auf neue Weise zu nutzen, um Menschen zu einem längeren und besseren Leben zu verhelfen. Lass Dich inspirieren, wer wir sind, was wir tun und wie wir es tun. Absolviere Deine Ausbildung bei Roche und leiste damit einen entscheidenden Beitrag zum Wohle des Patienten!Lernen. Zukunft. Roche.Top Argumente für den JobDu kommst mit neusten Technologien in Berührung und hilfst mit bei der digitalen Transformation des UnternehmensDu klärst in enger Zusammenarbeit mit den Fachabteilungen die Bedürfnisse für neue technische Lösungen ab, erarbeitest mögliche Lösungsvarianten und ermöglichst so Forschung, Entwicklung und Produktion moderner PharmaprodukteDeine Lösungen werden im Team geplant, realisiert und getestet. Anschliessend schulst und unterstützt du die Anwender nach Übergabe des SystemsDu bist für die Wartung und den reibungslosen Betrieb des Systems verantwortlich Dein SpezialgebietAls Informatiker:in mit Fachrichtung Applikationsentwicklung fokussierst du dich auf den Entwurf, die Entwicklung und den Betrieb moderner und innovativer Software Lösungen.Dein ProfilDu kennst Dich gut mit Computern aus und hast auch schon erste Programmiererfahrung gesammelt? Prima!Du stellst Dich gerne neuen Herausforderungen? Perfekt!Du möchtest dein Wissen rund um digitale Technologien und technische Abläufe ausbauen? Dann sollten wir uns kennenlernen!Was du mitbringen solltest:Du interessierst Dich für Computer und digitale Technologien, sowie technische Zusammenhänge und betriebliche AbläufeDu arbeitest gerne im Team, beteiligst Dich aktiv an Diskussionen und hast Spass daran, kreative Lösungsansätze zu finden, kannst aber auch selbständig und konzentriert für Dich arbeitenDu bist experimentierfreudig, analysierst gerne und besitzt ein abstraktes Denk- und VorstellungsvermögenDas Strukturieren und Planen von Abläufen fällt dir leicht und Du verfügst über eine exakte, zuverlässige und eigenverantwortliche ArbeitsweiseDas Tastaturschreiben und weitere gängige Anwendungen am PC bereiten dir keine MüheGute Leistungen in Mathematik, Medien und InformatikMindestens Schulniveau Sek E (BS/BL/SO), Sek (AG), Mittlere Reife (D) oder höhere SchulstufenDeutsch: Muttersprache oder Niveau B2 und Englischkenntnisse GrundniveauDeine VorteileDu arbeitest in einer internationalen Umgebung und erhältst erstklassige Einblicke in die Unternehmung und den BerufsalltagDu besuchst eine praxisorientierte WerkschuleDu arbeitest mit hochmodernen Anlagen, Geräten und zukunftsorientierten EinrichtungenBei entsprechenden Leistungen besteht die Möglichkeit, dass wir dich nach der Ausbildung bei diversen Weiterbildungsmöglichkeiten unterstützen Je nach Distanz zum Arbeitsort hast du die Möglichkeit in Basel ein Zimmer im Roche Wohnhaus zu bekommenDeine vollständige Bewerbung enthält folgende Dokumente:LebenslaufZeugnisse der letzten zwei SemesterCheck S2, falls du aus dem Bildungsraum Nordwestschweiz kommst (falls vorhanden)Wichtig: Bitte achte auf die Vollständigkeit deiner Bewerbung. Es können nachträglich keineDokumente hochgeladen werden.Neurodiversität: Alle Bewerbungen werden nach denselben, fairen Eignungskriterien bewertet. Solltest du aufgrund von Neurodiversität (z.B. ADHS, Autismus-Spektrum) oder anderen Besonderheiten spezifische Bedürfnisse für das Bewerbungsverfahren oder die Lehre haben, bitten wir dich, uns dies spätestens beim Bewerbungsgespräch transparent mitzuteilen. Diese Transparenz ermöglicht uns, die Qualität deiner Betreuung während des Interviews und der Lehre optimal zu gewährleisten. Deine Angaben werden selbstverständlich streng vertraulich behandelt.Kontakt: Elias Hammel Who we areA healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.Let’s build a healthier future, together.Roche is an Equal Opportunity Employer.

Basel

Lehrstelle als ICT-Fachmann:frau EFZ (ab August 2027)

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.The PositionWichtig: Nach deiner Bewerbung melden wir uns innerhalb weniger Tage per E-Mail bei dir. Um sicherzustellen, dass du keine wichtige Nachricht verpasst, bitten wir dich, neben deinem Posteingang auch den Spam- oder Junk-Ordner zu prüfen. Falls du innerhalb einer Woche nichts von uns hörst, melde dich unter basel.berufslehre@roche.com.Der BerufAls ICT-Fachmann:frau bei Roche bist du verantwortlich für die Installation und Konfiguration von PCs, Tablets und Mobiltelefonen und stellst sicher, dass diese ordnungsgemäss und sicher funktionieren. Du bist auch zuständig für den Anschluss von Peripheriegeräten wie Notebooks und Drucker an die Netzwerkinfrastruktur und löst auftretende Störungen. Im IT-Support arbeitest du eng mit den Endbenutzern zusammen und berätst sie bei der optimalen Nutzung von ICT-Systemen und -Werkzeugen. Bei auftretenden Problemen analysierst du diese gründlich und arbeitest eng mit anderen Spezialisten zusammen, um passende Lösungen zu finden. Darüber hinaus übernimmst du administrative Aufgaben wie ICT-Bestellungen und unterstützt Kunden beim Beschaffungsprozess von ICT-Geräten.Die AusbildungZu Beginn deiner dreijährigen Lehre als ICT-Fachmann / ICT-Fachfrau EFZ lernst Du zunächst in der Werkschule die Computer- und Netzwerk-Grundlagen kennen. Nach einer Einführung in die Roche IT-Umgebung kannst du bereits erste Aufgaben im IT Support übernehmen. Du lernst wie man in Service Teams arbeitet und wirst im Laufe der Lehrzeit praktische Erfahrung in mindestens zwei der folgenden Bereiche sammeln:IT Experience Center Basel/Kaiseraugst: Beratung von Endbenutzern beim Umgang mit den Roche IT SystemenLabor Support in der Forschung – Einsatz im pRED Center in Basel: Integration von Laborgeräten in die IT-InfrastrukturLabor Support in der Produktion: Integration von Endbenutzer Geräten wie PC’s und Drucker in den Produktionsbetrieb. Je nach persönlichem Interesse können während der gesamten Lehrzeit weitere Themenbereiche eigenverantwortlich erarbeitet und vertieft werden. Die AnforderungenMittleres Schulniveau (Ausnahmen für sehr gute Leistungen im Basisniveau) Deutsch Muttersprache oder Niveau B2 und Englischkenntnisse GrundniveauDu interessierst dich für technische und mechanische ZusammenhängeDu arbeitest gerne im Team und bist offen für NeuesDu verfügst über eine exakte, zuverlässige und systematische ArbeitsweiseDu bist gut im Organisieren und hast ein hohes Dienstleistungsbewusstsein Die WeiterbildungsmöglichkeitenNach der erfolgreichen Ausbildung gibt es verschiedene Weiterbildungsmöglichkeiten an der Höheren Fachschule (HF), Fachhochschule (FH) oder Universität. Für die Letzteren braucht es eine Berufsmaturität, für die Universität zusätzlich noch eine Passerelle.Nachfolgend einige Weiterbildungsmöglichkeiten:BerufsmaturitätBM1 (lehrbegleitend, nach Absprache)BM2 (nach der Ausbildung)Fortbildungskurse von Firmen und BerufsverbändenBerufsprüfung (BP) mit eidg. Fachausweis:ICT-Applikationsentwickler:inICT-System- und Netzwerktechniker:inWirtschaftsinformatiker:inMediamatiker:inCyber Security Specialist mit eidg. FachausweisDigital Collaboration Specialist mit eidg. FachausweisHöhere FachprüfungDipl. ICT-Manager:inDipl. ICT Security ExpertHöhere FachschuleBildungsgänge im Fachbereich Informatik, z. B. Wirtschaftsinformatiker:in HF, Informatiker:in HFFachhochschuleStudiengänge im Fachbereich Informatik, z. B. Bachelor of Science in Informatik oder in Wirtschaftsinformatik. Je nach Fachhochschule gelten unterschiedliche Zulassungsbedingungen.Deine VorteileDu arbeitest in einer internationalen Umgebung und erhältst erstklassige Einblicke in die Unternehmung und den BerufsalltagDu besuchst eine praxisorientierte WerkschuleDu arbeitest mit hochmodernen Anlagen, Geräten und zukunftsorientierten EinrichtungenBei entsprechenden Leistungen besteht die Möglichkeit, dass wir dich nach der Ausbildung bei diversen Weiterbildungsmöglichkeiten unterstützen Je nach Distanz zum Arbeitsort hast du die Möglichkeit in Basel ein Zimmer im Roche Wohnhaus zu bekommenDeine vollständige Bewerbung enthält folgende Dokumente:LebenslaufZeugnisse der letzten zwei SemesterCheck S2, falls du aus dem Bildungsraum Nordwestschweiz kommst (falls vorhanden)Wichtig: Bitte achte auf die Vollständigkeit deiner Bewerbung. Es können nachträglich keineDokumente hochgeladen werden.Neurodiversität: Alle Bewerbungen werden nach denselben, fairen Eignungskriterien bewertet. Solltest du aufgrund von Neurodiversität (z.B. ADHS, Autismus-Spektrum) oder anderen Besonderheiten spezifische Bedürfnisse für das Bewerbungsverfahren oder die Lehre haben, bitten wir dich, uns dies spätestens beim Bewerbungsgespräch transparent mitzuteilen. Diese Transparenz ermöglicht uns, die Qualität deiner Betreuung während des Interviews und der Lehre optimal zu gewährleisten. Deine Angaben werden selbstverständlich streng vertraulich behandelt.Kontakt: Elias Hammel Who we areA healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.Let’s build a healthier future, together.Roche is an Equal Opportunity Employer.

Basel

Senior Software Engineer Lab Automation

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.The PositionAdvances in AI, data, and computational sciences are transforming drug discovery and development. Roche’s Research and Early Development organisations at Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel computational models to drive impact. Seamless data sharing and access tomodels across gRED and pRED are essential to maximising these opportunities. The newComputational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness this transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients Worldwide.Within the CoE organisation, the Data and Digital Catalyst (DDC) organisation drives the modernisation of our computational and data ecosystems and integration of digital technologies across Research and Early Development to enable our stakeholders, power data-driven science and accelerate decision-making.As a senior lab automation software engineer, you will be the essential link to the automation scientists in the lab. Using your background in both software development and hardware integration, you will work with a team of software-focused engineers to build, test and do what is needed to bring the software and hardware layers into production.The OpportunityTo excel in this role, you will bridge the gap between complex software engineering and laboratory research in drug discovery through the following responsibilities:Design, program and troubleshoot high-throughput lab workflows.Build orchestration systems, hardware abstraction layers, and instrument drivers that manage retries and allow unattended operation.Implement logging, metrics, and alerts across hardware and software to identify failures. Fix root causes using software or vision models instead of relying on manual workarounds or vendor support.Build systems to maintain a digital representation of the lab, including sample identity, instrument state, and resource availability. Connect instruments via APIs and integrate with LIMS and ELNs.Manage hardware requirements, site constraints, reagent selection, and work cell integration from initial design to deployment.Work directly with software engineers, automation scientists, and hardware engineers to turn scientific processes into technical architectures.Who You AreYou have 5+ years of experience in software engineering and hardware integration.Experienced in programming commercial liquid-handling or laboratory automation platforms and integrating robotic manipulators.Proficient in C# or Python for building software and integration frameworks.Familiar with molecular biology, biochemistry, or wet lab workflows to help translate scientific needs into engineering solutions.Prototyping design experience, including CNC milling, laser cutting, and CAD.A clear communicator who collaborates with scientists and multidisciplinary teams to build complete solutions.Skilled at using APIs and SDKs to interact with complex laboratory software ecosystems.Experienced in designing workflow orchestration or scheduling systems that manage shared resources, dependencies, and priorities.Preferred skills and experienceSkilled with computer vision models (such as OpenCV, YOLO, or SAM) for automated error handling and object or anomaly detection.Experienced in training, evaluating, or adopting AI/ML models, including reinforcement or imitation learning for robotics.Capable of building and evaluating AI-enabled systems, defining evals, establishing guardrails for determinism versus nondeterminism, and measuring reliability.Knowledgeable about sensors, microcontrollers, and task-and-motion planning.Familiar with cloud infrastructure and digital twin simulation.A cover letter is not necessary, you will be required to fill a questionnaire. Ready to take the next step? We'd love to hear from you. Apply now to explore this exciting opportunity! #ComputationCoE Where pay transparency applies, details are provided based on the primary posting location. For this role, the primary location is Basel. If you are interested in additional locations where the role may be available, we will provide the relevant compensation details later in the hiring process.Who we areA healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.Let’s build a healthier future, together.Roche is an Equal Opportunity Employer.

Basel

Principal / Senior Principal Software Engineer

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.The PositionA healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche.Advances in AI, data and computational sciences are transforming drug discovery and development. Roche’s Research and Early Development organizations at Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel computational models to drive impact. Seamless data sharing and access to models across gRED and pRED are essential to maximising these opportunities. The Computational Sciences Center of Excellence (CS CoE) is a strategic, unified group whose goal is to harness the transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and life-changing medicines for patients worldwide.Within the CS CoE organisation, the Data and Digital Catalyst (DDC) organization leads the modernization of our computational and data ecosystems by integrating digital technologies across Research and Early Development to empower stakeholders, advance data-driven science and accelerate decision-making.The Solutions team within the DDC Organization develops modernized and interconnected computational and data ecosystems. The Data Ecosystem is foundational to building solutions that accelerate the work done by our Computational and Bench Scientists and enable ML/AI tool creation and adoption. Our team specializes in building Data Pipelines and Applications for data acquisition, collection, storage, transformation, linkage and sharing. Join our Data and Digital Catalyst team as a Software Engineer, where you will develop the modernized and interconnected computational and data ecosystems that are foundational to our research. You'll build robust and scalable systems that unlock the potential of our diverse scientific data, directly accelerating the discovery and development of life-changing treatments for patients. This is a unique opportunity to empower our scientists and advance data-driven science through innovative technology.The OpportunityDesign and build interactive tools for both small and large molecule drug discovery integrating data, molecular design workflows, computational algorithms, and AI models.Build and enhance a modern, scalable ecosystem of applications and tools to capture, move, and prepare scientific data for analysis.Design and deliver complex, user-friendly data applications and pipelines that integrate diverse data sets across key scientific domains.Leverage standard patterns like microservices and event-driven architecture to improve our data workflows and application ecosystem.Champion technical excellence by ensuring our solutions are innovative, best-in-class, and seamlessly integrated.Integrate diverse data sets to power Artificial Intelligence (AI), machine learning (ML), and Natural Language Search capabilities.Collaborate directly with computational and research scientists to understand their challenges and translate them into effective technology solutions.Provide technical leadership on ongoing initiatives and identify new opportunities to build common, reusable solutions.Mentor junior developers, fostering their professional growth and upholding high engineering standards.Who You AreWe are looking for a passionate and collaborative software engineer with experience building scalable platforms for drug discovery or a related domain. You thrive on engaging with scientific partners to solve complex challenges and are dedicated to engineering best practices.A Ph. D. or equivalent experience of 8-10+ years working in life science domain building full-stack software solutions, preferably for drug discovery and strong software engineering expertise in all layers of stack including backend (e.g., Python, Java) and frontend (e.g., React, Vue) is required.Deep experience with modern data engineering, including databases (SQL/NoSQL), data engineering (ETL/ELT), and APIs (REST, GraphQL)Proven experience developing and deploying applications on cloud-native architectures, preferably AWS and experience in setting up SDLC best practices for the team including versioning, testing, observability, CI/CD, etc. Exceptional abilities to architect scalable solutions in complex environment with multiple existing system integrations and demonstrated proficiency in applying AI-assisted and agentic coding practices, both as an individual contributor and collaboratively within a team environment.Outstanding communication and collaboration skills, with the ability to articulate technical concepts to diverse audiences.Preferably experience working in pharmaceutical or a related domain and in setting best-practices for agentic coding producing maintainable code.The Global Grade for this role can be: SE7 or SE8 to align with Principal / Sr. Principal Engineer#ComputationCoE#tech4lifeComputationalSciences Who we areA healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.Let’s build a healthier future, together.Roche is an Equal Opportunity Employer.

Basel

Senior Principal Cybersecurity Engineer

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.The PositionData security and privacy are key success factors in our digital transformation and essential to reach our ambitions. You are inspired to contribute to the overall Roche Diagnostics vision by applying end-to-end Division-wide product security and privacy operations to keep our products and services secure and privacy compliant throughout the entire lifecycle. You believe in the potential of science, technology, data, and insights to improve the standard of care for humankind, and you are eager to help navigate through uncharted territory to lift this potential.The Opportunity:Define robust security and privacy baselines: Establish comprehensive security and privacy requirements for Roche medical devices, health/clinical solutions, and cloud or on-premises products across the entire Software Development Lifecycle (SDLC).Champion risk management frameworks: Contribute to the development and implementation of the product lifecycle security and privacy risk management framework, integrating changes in technology, customer needs, and global regulations.Lead threat modeling and risk evaluations: Perform threat modeling and cybersecurity risk management assessments to actively safeguard patient safety, customer property, and critical business continuity.Drive proactive vulnerability management: Oversee pre- and post-market vulnerability handling across all technology layers, ensuring timely remediation and alignment across relevant platforms.Assess and mitigate testing outcomes: Evaluate risks identified through security testing activities (including SAST, DAST, SCA, IaC, and penetration testing) and steer direct remediation activities with engineering teams.Coordinate independent validations and incident response: Plan and coordinate external security verification and validation (such as penetration tests) while supporting security incident response and forensic activities in direct partnership with Roche Intelligence and Defense teams.Maintain regulatory compliance documentation: Author and maintain high-quality internal and external compliance documentation, playbooks, and standardized tools for audit-readiness and quality excellence.Escalate and steer strategic capabilities: Present clear risk evaluations, impacts, and mitigation proposals to executive risk committees, while leading strategic cross-functional initiatives that elevate Division-wide product security.Who you are:Education: Bachelor’s degree in Engineering, Computer Science, or a related discipline (Master's or PhD preferred).Years of Experience:BS with 12+ years of relevant experience in similar roles (with a minimum of 7+ years in security engineering, security operations, vulnerability management, or application security), ORMS with 8+ years of relevant experience in similar roles, ORPhD with 4+ years of relevant experience in similar roles.Technical & Platform Expertise: Demonstrated track record working alongside product software development and cloud platform teams, ideally within international healthcare or highly regulated sectors.Assessment & Threat Modeling Mastery: In-depth proficiency in threat modeling, product security posture analysis, and deploying privacy controls to mitigate enterprise and clinical risks.Regulatory & Industry Standards: Comprehensive knowledge of industry standards and regulatory frameworks (ISO 27000 family, FDA Guidances, MDCG, HITRUST, GDPR, and CPRA); hands-on familiarity with global medical device submissions (e.g., FDA, CE Mark, NMPA) is strongly recommended.Certifications & Leadership: Relevant professional security certifications (such as CISSP, CSSP, CISM, CISA, CEH, SANS GIAC, or ISO 27001 Lead Auditor); proven ability to mentor, coach chapters, and build security champion networks across departments.Communication & Mobility: Fluency in English (verbal and written) with strong stakeholder-influencing capabilities across global, cross-cultural teams; German proficiency is a plus. Willingness to travel up to a maximum of 20%.Call to Action:Ready to bring your unique qualities to Roche and make an impact? Apply now and join us in our mission to shape the future of healthcare. Who we areA healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.Let’s build a healthier future, together.Roche is an Equal Opportunity Employer.

Rotkreuz

Data Scientist / Engineer - DNA-Encoded Library Technology (DELT)

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.The PositionIn Roche’s Pharmaceutical Research and Early Development organisation (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility, and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.Therapeutic Modality (TMo) organisation, accountable for translating disease biology into high-quality drug candidates across small molecules, large molecules, oligonucleotides, and genomic medicines. By integrating deep modality expertise with cross-disciplinary collaboration, TMo drives innovation within and across platforms to enable differentiated, sustainable therapeutic impact.The DELT team lies in Molecular Discovery Technologies within the Small Molecule Research Discovery (SMRD) department, which is part of Therapeutic Modalities (TMo) within Roche Pharma Research and Early Development (pRED). We deliver leading-edge science to drive the success of Roche’s early pipeline discovery research activities through strong expertise in high-throughput or focused screening platforms, DNA-encoded library technology (DELT), protein science & enzymology/biophysics, cell-based assays, biostructure determination, computer-assisted drug design, and medicinal chemistry. We are accountable for the provision of high-quality chemistry starting points for small-molecule projects and generating molecular and mechanistic insights that are critical for the advancement of discovery projects.The OpportunityWe are looking for a Scientific Data Scientist & Engineer – DNA-Encoded Library Technology (DELT) to join our team at the intersection of chemical biology, cheminformatics, and data science.In this role, you will help shape the next generation of data-driven DNA-Encoded Library Technology (DELT) by combining scientific data analysis, scalable data engineering, and advanced computational approaches. You will transform complex screening data into actionable scientific insights and develop robust, automated workflows that accelerate hit identification and support small-molecule drug discovery.Working closely with experimental scientists, computational chemists, and machine learning experts, you will bridge scientific innovation and practical implementation, enabling more informed, reproducible, and efficient decision-making across our DELT platform.Your impact:You advance our DELT data analytics by applying robust statistical methods, predictive models, and advanced analytical approaches to interpret large-scale DEL screening datasets, identify promising chemical starting points, and support hit and lead discovery programs.You develop intuitive, accessible analytical tools and workflows that empower DELT screening scientists and project teams to rapidly evaluate selection results, prioritise compounds, and make informed experimental decisions.You design, implement, and maintain automated, reproducible data processing and analysis pipelines that transform complex experimental outputs into reliable, decision-ready insights.You develop computational workflows and searchable building-block data resources to support chemical space exploration, reaction prediction, library design, and synthesis strategy optimisation.You partner closely with experimental scientists, computational chemists, and machine learning teams across Roche's small-molecule research organisation to translate evolving scientific challenges into scalable computational solutions.You communicate scientific insights by presenting analytical results, computational approaches, and technical developments clearly to scientific and multidisciplinary audiences, supporting knowledge sharing and adoption of new capabilities.You champion scientific excellence by promoting reproducibility, data integrity, and robust engineering practices while contributing to a safe and compliant research environment.Who you are You are highly passionate about DNA-encoded library technology, pushing the boundaries of the field, as well as discovering and taking on new challenges. We are looking for a highly motivated data scientist with a strong enthusiasm for chemical biology and pushing the technology to the next step, who is interested in performing state-of-the-art research in the pharmaceutical industry. You hold a PhD or M.S. in Bioinformatics, Statistics, Computer Science, Data Science, Cheminformatics, Software Engineering, or a related quantitative field.You have a strong software engineering background with experience deploying pipelines at scale in HPC or cloud platforms.You possess proven experience in high-throughput scientific data analysis (preferably with large-scale screening data, DEL selection outputs, or NGS processing pipelines) and a demonstrated ability to architect reliable, user-friendly tools that simplify complex analytical workflows for non-expert scientists.You demonstrate strong proficiency in Python and statistical programming, along with expertise in data visualisation frameworks (e.g., Spotfire, Tableau, or modern web dashboarding tools).You bring an understanding of hit-triaging, noise reduction, statistical ranking, and signal verification in large-scale datasets, with demonstrated capability in cheminformatics (including handling chemical structures, building-block metadata, or toolkits like RDKit/OpenEye) and laboratory data systems (LIMS, SQL, relational databases), integrating computational tools with experimental workflows as a plus.You are a critical thinker and problem solver with a continuous improvement mindset and a track record of conceptualising scalable scientific solutions, paired with strong communication skills to translate complex quantitative findings for multidisciplinary and non-quantitative stakeholders.At Roche, we aim high to deliver life-changing healthcare solutions. If you’re ready to make a meaningful impact on patients and healthcare systems worldwide, this is the place for you. Who we areA healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.Let’s build a healthier future, together.Roche is an Equal Opportunity Employer.

Basel

Scientist – Assay Data, AI & Workflows

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.The PositionIn Roche’s Pharmaceutical Research and Early Development organization (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility, and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.Therapeutic Modality (TMo) organization, accountable for translating disease biology into high-quality drug candidates across small molecules, large molecules, oligonucleotides, and genomic medicines. By integrating deep modality expertise with cross-disciplinary collaboration, TMo drives innovation within and across platforms to enable differentiated, sustainable therapeutic impact.The OpportunityWe are looking for a highly versatile Scientist to serve as our primary operational and computational architect embedded in the wet-lab scientific community. In this role, you will bridge the gap between physical laboratory benches and advanced digital infrastructure. You will have the chance to shape how active learning loops could fundamentally rethink small molecule assay development for screening and profiling by building future ready agentic AI workflows from assay design to data delivery. Concurrently, you will champion platform adoption across the department, ensuring bench scientists are trained and supported on core tools. This profile requires a unique combination of biological literacy and data engineering acumen to successfully design closed-loop analytical systems, minimize operational bottlenecks, and transition raw screening readouts into predictive, FAIR-compliant data assets.Lead the co-development, operational rollout, and continuous training for our end-to-end assay development and screening laboratory information management systems (LIMS), ensuring complete, traceable data trails and digital twins.Design and integrate cutting-edge Agentic AI tools and Design of Experiments (DoE) frameworks.Build and adjust pipelines that connect specialized raw instrument outputs directly with databases to achieve robust FAIR (Findable, Accessible, Interoperable, and Reusable) data standards.Act as a change agent by coordinating user onboarding, training bench scientists, and championing platform adoption across the broader scientific community.Make a direct impact by accelerating assay design and execution times, lowering processing error rates, and resolving operational bottlenecks for specialized teams.Who You AreYou hold a Ph.D. or M.S. in Computational Biology, Scientific Informatics, Bioinformatics, Biology/Biochemistry with a strong computational focus, or a related quantitative scientific discipline.You bring solid experience in cellular, biochemical, or biophysical systems and are familiar with FAIR data management standards.You have proven experience working with laboratory informatics environments (such as LIMS or electronic lab notebooks) alongside wet-lab operations incl. Design of Experiments.You demonstrate strong programming proficiency, including building or maintaining databases, automating data extraction, and working with ML/LLM API integration.You are a collaborative communicator with a customer-centric mindset, ready to train cross-functional users and manage stakeholder relationships effectively.At Roche, we aim high to deliver life-changing healthcare solutions. If you’re ready to make a meaningful impact on patients and healthcare systems worldwide, this is the place for you. Who we areA healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.Let’s build a healthier future, together.Roche is an Equal Opportunity Employer.

Basel

Internship: Generative AI Designer (as of January 2027 for 12 months in Rotkreuz)

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.The PositionCXSD, the Customer Experience and Solution Design team at Roche Diagnostics, is looking for a curious and hands-on Generative AI Designer Intern to join ARC (AI for Roche Creators), a newly formed squad exploring the future of design at the intersection of creativity and AI technology. ARC builds AI augmented workflows, tools and prototypes that help designers, researchers and engineers move from idea to working experience 10x faster. As a Generative AI Designer, you will help move our design community from static digital prototypes to vibe coded prototypes that look, feel and behave like real products. You will turn concepts into functional prototypes using AI coding tools such as Claude Code, as well as generative tools for image, video, 3D and audio, and help define how a global design organization adopts generative AI in its daily work.You will work closely with senior designers, human factors engineers, technologists and software engineers, learning how business requirements, regulatory constraints and user needs translate into design decisions in a healthcare context. You will be part of a design organization of more than 80 professionals who aim to transform the healthcare industry for the better.The OpportunityHelping shift the way our designers prototype allows you to move from static, click-through mockups to vibe-coded prototypes built with real logic, real data, and real interactions.You prototype quickly by turning ideas, user needs, and design concepts into functional prototypes, visual concepts, motion studies, and 3D explorations using the right mix of generative tools.Close partnership with designers and researchers enables you to understand their workflows and identify high-value opportunities where AI can augment, rather than replace human creativity.Building small internal tools, plugins, and workflows using our One Design System and design tokens forms a core part of your efforts to speed up the design process.You help bridge experimental prototypes and production-ready solutions by translating design needs into clear technical requirements for engineering teams.Your hands-on support in usability testing covers the full lifecycle of prototypes across planning, preparation, conducting, and analyzing sessions.Joining a highly motivated and very kind team, you evaluate new AI models, tools, and techniques to share learnings with the wider design community, while contributing to demos, workshops, and training materials that help designers of all technical levels start vibe-coding their own prototypes.Who you areYou are currently enrolled at a university or have graduated within 12 months prior to the start of the internship in the fields of Interaction Design, UX Design, HCID, Computer Science, Creative Technology, Industrial Design, or a similar field.Hands-on experience with generative AI tools covers both AI coding tools such as Claude Code and generative media tools for image, video, 3D, or audio, with showcasing at least one project being required.You are comfortable with front-end basics including HTML, CSS, JavaScript/TypeScript, and React, allowing you to read, adapt, and debug the code that AI tools generate.A solid design foundation in UX, UI, and interaction design along with practical experience in Figma is essential, with showcasing a project being required.You understand how design systems and design tokens work, such as Material Design.A fast learning mindset drives you to enjoy experimenting and naturally share what you build with others.Fluency in English is required to collaborate and communicate design ideas clearly within an international, cross-functional team.Valuable nice-to-have assets include experience with node-based or visual AI workflow tools, LLM APIs, building simple AI agents, work with Arduino, Processing, or physical computing for experiences beyond screens, and active participation in the AI or design community through (side projects, open source, talks, posts).Application ProcessPlease upload your CV (in English) along with a certificate of enrolment (if you are currently studying) or your degree certificate (if you have already completed your studies).We look forward to receiving your portfolio - please make sure to include links to live prototypes or repositories where possible.Non-EU/Non-EFTA citizens must attach a confirmation from the university to the application documents, stating that a mandatory internship is part of the education and be continuously enrolled in their university for the whole duration of this internship.Additional InformationPlease note that this position is designed purely as a practical internship, so writing an academic thesis alongside it is unfortunately not possible.The preferred start date for this internship is January 2027, or upon discussion. Duration: 6-12 monthsReady to take the next step? We'd love to hear from you. Apply now to explore this exciting opportunity! Who we areA healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.Let’s build a healthier future, together.Roche is an Equal Opportunity Employer.

Rotkreuz

International Product Manager, Molecular Workarea

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.The PositionAs the International Product Manager (IPM) in the Molecular Work area portfolio, you will be at the center of managing the global strategy for the cornerstone of modern molecular diagnostics. Reporting to the International Business Leader, you will shape the future of these market-leading platforms and the wider PCR Systems portfolio. Your passion for driving the success of life-changing diagnostic solutions will be key. You enjoy fostering a culture of global collaboration, working with diverse teams to maintain and grow our market leadership.The OpportunityLead the development and execution of the global product strategy for the Molecular Workarea portfolio, ensuring long-term market leadership and alignment with the overall Molecular Work Area vision.Collaborate with cross-functional teams (R&D, Global Customer Support, Operations) to drive the full product lifecycle, from new feature development and on-market support to long-term strategic planning.Gather customer and business requirements from affiliates, key customers and other Lifecycle Teams, translating them into compelling business cases and product features that differentiate our systems in the market.Act as the product champion and central point of contact for regional and affiliate partners, ensuring they have the tools, training, and support needed to succeed commercially.Serve as an active and influential member of the Product Care & Quality Team (PCQT), driving the prioritization and resolution of on-market issues to ensure customer satisfaction and product quality.Drive the strategic marketing direction for the portfolio. Partner with Global Marketing Manager(s) to define positioning, messaging, and launch strategies that resonate in a competitive market. You will own the competitive analysis, translating insights into powerful countermeasures and high-impact campaigns.Who you areBachelor's degree in a Scientific, Engineering, or Business discipline; MBA preferred.A >5 years of product management, marketing, or related commercial experience within the Medical Diagnostics or Device industry.Fluent in English.Proven ability to prioritize requirements and make strategic trade-off decisions, with effective communication to diverse global stakeholders.Strong leadership, negotiation, and influencing skills, with experience working in multidisciplinary teams within a global matrix environment to develop strategy and articulate a clear investment vision.Direct experience with the cobas® 5800/6800/8800 systems or other automated molecular diagnostic platforms.Strong understanding of IVD instrument hardware, software, and overall laboratory workflows, including LIS/middleware interfacing.Global experience, e.g., has worked in a global role or has experience working directly with multiple country affiliate or business unit environments.Understanding of the fundamentals of design control processes for the development of regulated medical devices.Are you interested? We look forward to receiving your application Who we areA healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.Let’s build a healthier future, together.Roche is an Equal Opportunity Employer.

Rotkreuz

Internship - Software and Data Engineer (for 12 months in Rotkreuz)

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.The PositionAs a Digital & Analytics Intern at Roche Diagnostics in Rotkreuz, Switzerland, you will join an innovative team solving operational challenges through data, digital products, and AI. Working in a hybrid model, you will contribute across the entire solution lifecycle—from problem identification to prototyping and adoption. Designed for candidates with backgrounds in Data Engineering or Data Analytics & Science, your assignment will be tailored to your strengths and project needs (expertise in every listed technology is not required).This internship position is located in Rotkreuz, Switzerland, with a hybrid working model.The Opportunity:You work with business and process experts to understand operational challenges, identify opportunities, translate them into clear requirements and define what success looks like.You design and build dashboards, analytical applications and lightweight web applications using technologies such as Python, R or TypeScript, with frameworks such as React or FastAPI where appropriate.You develop and improve reliable data pipelines and transformations using technologies such as SQL, Airflow and dbt.You contribute to automation, DevOps and CI/CD practices, including testing, deployment and maintainable development workflows.You contribute to solution concepts, prototypes and feasibility assessments together with experienced team members and stakeholders.You contribute to data governance, data quality and digital engineering standards to support reliable and compliant solutions.You communicate technical concepts and findings clearly to technical and non-technical stakeholders through documentation, demos and presentations.You work with Product Care data across areas such as supply, quality and engineering, improving data availability and supporting better operational decisions.Who You Are:You are currently enrolled in a Master’s degree or have completed a Bachelor’s degree within the last 12 months prior to the internship start date, preferably in Computer Science, Business Informatics, Data Science, Artificial Intelligence, or a related field.You bring practical experience with at least one programming language such as Python, TypeScript, or R, alongside basic experience with SQL and working with data.You bring experience developing an application, analytical solution, or substantial software project through your studies, work experience, or personal projects.You possess strong communication skills and fluent English, enabling effective collaboration. German is nice to have.You possess a high level of problem-solving competence, strong analytical skills, and the ability to work independently, learn quickly, and collaborate effectively with others.An understanding of basic software-design principles and an interest in modern software engineering and AI is considered an asset.Hands-on experience with Git, CI/CD, or automated testing, and exposure to technologies like React, FastAPI, dbt, or Airflow is preferred. Experience with AI agents, data visualization, or building data products is nice to have.Additional information:Start Date & Duration: The preferred start date for the internship is January 2027 with a duration of 12 months or upon discussion.Workload: Flexible working options from 80% to 100% full-time equivalent are open for discussion.Thesis Note: Please note that the internship cannot be combined with a university thesis.Application Process:Please upload your CV (in English), a motivation letter with your application, and a certificate of enrolment (if you are currently studying) or your degree certificate (if you have already completed your studies).Non-EU/Non-EFTA citizens: Must attach a confirmation from the university to the application documents, stating that a mandatory internship is part of the education and be continuously enrolled in their university for the whole duration of this internship.Ready to take the next step? We'd love to hear from you. Apply now to explore this exciting opportunity! Who we areA healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.Let’s build a healthier future, together.Roche is an Equal Opportunity Employer.

Rotkreuz

Scientific Digital Product Lead, Assay Workflows

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.The PositionA healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche.Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche’s Research and Early Development organisations at Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel computational models to drive impact. Seamless data sharing and access to models across gRED and pRED are essential to maximising these opportunities. The new Computational Sciences Center of Excellence (CS CoE) is a strategic, unified group whose goal is to harness this transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide. The Data and Digital Catalysts (DDC) department within the CS CoE is a diverse, curious and action-driven team at the intersection of science, engineering, and computation and with ambition to advance our technical excellence. The team focuses on partnering with scientific communities to build a robust computational and data ecosystem that fuels scientific discovery and enables faster, data-informed decision-making. We aim to modernize our ability to acquire, store, link, share, find, and analyze data across the organization through scalable, integrated, and forward-looking solutions that truly make every data point count.Reporting to the Domain Head of Assay Workflows within DDC, this Scientific Product Lead will play a pivotal role in fostering strong partnerships with RED stakeholders, developing a deep understanding of the “why,” and strategically prioritizing the “what” and “when” into an actionable roadmap that delivers meaningful outcomes. The Product Lead will work in close collaboration with the DDC capability teams, shaping the “how” and aligning the “who” to deliver technical excellence, ensuring the development of integrated, innovative, and best-in-class products and platforms that accelerate scientific discovery within the REDs. This is an exciting opportunity to advance cutting-edge lab workflows and innovative solutions, making a meaningful impact on Roche’s mission to deliver innovative therapies to patients.The OpportunityJoin Roche’s Assay Workflows domain and drive the next generation of drug discovery platforms. As Scientific Digital Product Lead, you will bridge cutting-edge science and digital innovation—translating complex laboratory workflows into scalable, automated, and AI-powered platforms. You will act as the strategic engine behind our data infrastructure, building sustainable pipelines that empower both experimental scientists and advanced AI/ML research teams. If you possess deep domain expertise in preclinical R&D, proven digital product leadership, and a passion for applying AI to accelerate therapeutic breakthroughs, this is your chance to join the Assay Workflows team.Develop and refine the product family strategy within the Assay Workflows domain, ensuring alignment with key strategic initiatives. Enable seamless integration of products (applications/platforms) into our evolving data and digital ecosystem while contributing to the consolidation and deprecation of legacy systems, resulting in a reduction of technical debt.Demonstrate a deep understanding of the needs of scientists, applying strong data and digital acumen to shape existing and the next generation of products. Leverage this understanding to guide cross-functional teams, nurture stakeholder partnerships, and manage their expectations, ensuring the execution of initiatives that deliver tangible value to our scientists.Collaborate with technical/engineering and data experts to guide and enable the development of assay data workflows that incorporate scalable automation and modular concepts, driving faster and higher-quality insights from preclinical data.Understand and translate the needs of scientists and the business into actionable plans. Drive business analysis, demonstrate advanced product and program/project management skills, prioritize tasks within a given framework, effectively manage budgets, and oversee external workforce contributions.Boldly advocate for future-facing solutions by anticipating emerging capabilities and integrating them into strategic roadmaps. Identify key trends, technologies, and methodologies to ensure innovation and long-term competitiveness.Build and cultivate trusted internal and external partnerships with collaborators, fostering effective teamwork in a global setting.Be willing to span the domain and contribute where needed, even outside of your core area of expertiseWho You AreAt Roche, we seek individuals who are inspired by our mission and thrive in a culture defined by curiosity, innovation, and an entrepreneurial mindset. We recognize that our employees are essential to our success in delivering transformative medicines to patients. That’s why we are dedicated to fostering an exceptional workplace that fuels your growth, encourages meaningful collaboration, and empowers you to create a lasting impact on global healthcare.The ideal candidate will meet many of the following requirements:You hold a PhD or Master’s degree in life sciences, computer science, or a related field, with 3+ years of relevant professional experience in drug discovery, with a strong emphasis on data and digital innovation.You have deep scientific knowledge in Pharma R&D, including preclinical assay workflows, preclinical imaging (Digital Pathology, Biomedical Imaging, Optical Screening, Research Microscopy), and complex vitro models. Technical and engineering skills (e.g., Python, vibe-coding workflow development) are a strong advantage. You are a quick learner who excels at embracing new challenges and driving scientific and computational innovation across complex scientific domains by applying rapidly evolving new AI technologies. You demonstrate a strong combination of strategic vision and operational excellence, balancing long-term planning with hands-on execution to deliver impactful outcomes. You excel in navigating highly ambiguous or evolving situations with adaptability and focus.You have a proven ability to lead large-scale, cross-functional projects involving multiple teams and stakeholders. Experience in platform strategy, advanced product management, business analysis, and change management is highly valued, with prior work in a drug discovery setting strongly preferred.You are an exceptional collaborator, capable of navigating complex organizational landscapes, communicating clearly across diverse audiences, and translating big-picture transformation strategies into actionable, incremental steps that drive measurable progress.You have a forward-thinking and agile mindset, with a passion for innovation and curiosity. You are adept at integrating cutting-edge technologies and methodologies into assay workflows, prioritizing value creation, and fostering a culture of continuous improvement. Who we areA healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.Let’s build a healthier future, together.Roche is an Equal Opportunity Employer.

Basel

Student Internship in Device Development and Verification Engineering (Basel, 9-12 months)

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.The PositionThe global Device Development unit at F. Hoffmann-La Roche is responsible for the development of medical devices, combination products for R&D portfolio drug products. The department’s activities comprise a wide range of engineering disciplines ranging from the initial definition of product requirements to first commercialization and subsequent product care considering required regulatory, legislative, ecological, economical and technical aspects.Within the department, the Section Verification Engineering is responsible for the generation and management of experimental and cGMP verification activities providing objective evidence that the medical device/combination products perform according to patient`s and technical expectations. Thereby, Verification Engineering supports the evaluation, selection, design, development, characterization, and industrialization of medical devices, combination products and packaging systems (e.g., pre-filled syringe, needle safety device, autoinjector, infusion pump, blisters, bottles, new & break-through & platform technology, special packaging).The OpportunityAs an intern, you will be part of the Verification Engineering Section. During your internship you will be assigned to mentors, to research and coordinate a significant project including:technical assessment and implementation of new equipmentassess parameters impacting primary packaging/device functionality perform tests including statistical evaluation to assess method comparability / capabilities (proof-of-concept study, Design of Experiment)develop test methods summary and presentation of resultssupport practical testing for related projectsWho You AreYou are an enrolled Bachelor's or Master's student, or you have received your degree within the last 12 months, pursuing a qualification in pharmaceutical sciences, physics, chemistry, engineering, materials science or a comparable subject. You are someone who wants to influence your own development, and you are looking for a company providing the opportunity to pursue your interests across functions and geographies - where a job title is not the final definition of who you are, but the starting point. Furthermore, you have:already gained first experience with measurement systems and their application in the development of medical devices, combination products or packaging systemsfluent spoken and written English knowledge excellent documentation, presentation and interpersonal skills good user skills in standard office IT packagesAdditional preferred skills include:demonstrable practical knowledge of laboratory hands-on work and developing test methods for a given applicationexperience of working in pharma or other closely-regulated environment experience with numerical simulations of physical processesgood knowledge of statistical techniques and scientific writing German knowledge is of advantageApplication processPreferred start date: 1. February 2027Duration: 9 - 12 monthsPlease apply with a valid certificate of enrollment or degree certificate, a cover letter and a CV.Non EU/EFTA citizens are required to upload a certificate of mandatory internship in addition.Ready for the next step? We look forward to hearing from you. Apply now to discover this exciting opportunity! Who we areA healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.Let’s build a healthier future, together.Roche is an Equal Opportunity Employer.

Basel

Senior, AI Engineer - (Imaging)

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.The PositionAs an imaging-focused machine learning engineer within the AI Enablement team, you will be working closely with folks that span the gamut across computational scientists, biologists, bench scientists, AI/ML experts, product leaders, software engineers, and everyone in between. Your work will help bridge scientific intuition with quantitative analysis, enable richer phenotypic analysis, and provide new multimodal capabilities across large-scale, state-of-the-art datasets. You'll build, own, and constantly improve scalable AI/ML and computer vision systems that unlock the potential of our diverse scientific imaging data (e.g., microscopy, digital pathology, biomedical imaging, etc), accelerating the discovery and development of life-changing treatments for patients.The OpportunityDesign, develop, and test robust, scalable, and maintainable AI/ML scientific web applications and backend pipelines tailored for high-throughput scientific imaging data processing and visualization.Build, evaluate, and fine-tune state-of-the-art computer vision and deep learning models (e.g., cell segmentation, cell classification, phenotypic profiling, tissue segmentation, feature extraction, and image registration) applied to biological and clinical imaging modalities.Build tools to evaluate AI/ML and vision model performance, establish benchmark datasets, and quantify model quality, robustness, and drift over time.Develop and maintain scalable cloud infrastructures and data pipelines for collecting, structuring, storing, and accessing large-scale multi-dimensional imaging datasets (e.g., OME-TIFF, Zarr, HDF5).Contribute to architectural decisions, code reviews, and the evolution of engineering and MLOps processes for computer vision models.Stay up-to-date with emerging computer vision technologies and industry best practices while promoting a culture of continuous learning, collaboration, and curiosity.Who You ArePhD, Master’s with 3–5 years, or Bachelor’s with 4–7 years experience with a degree in Computer Science, Biomedical Engineering, Electrical Engineering, Computational Biology, or a related technical field with focus on machine learning engineering and computer vision.Strong proficiency with AI/ML frameworks and computer vision libraries (e.g., PyTorch, TensorFlow, OpenCV, MONAI, Scikit-Image, torchvision, Napari, or Bio-Formats).Deep expertise in computer vision algorithms (e.g., CNNs, Vision Transformers, UNet, SAM/Segment Anything, Cellpose).Expert knowledge of machine learning theory, image processing fundamentals, object detection, instance segmentation, and quantitative image analysis.Demonstrated experience working with high-dimensional scientific imaging data (e.g., fluorescence/brightfield microscopy, digital pathology whole slide images, high-content screening, multiplexed imaging, etc).Experience with Kubernetes, relational databases, NoSQL databases, object storage, and cloud-native architectures in public clouds (ideally AWS).Excellent communication skills and ability to build trusted partnerships with scientific collaborators, bioimage analysts, and cross-functional teams.Experience with multi-modal data fusion (combining scientific imaging with genomics, transcriptomics, or clinical tabular data) or in a pharma/biotech research environment.Experience with workflow automation, GenAI, Vision-Language Models, and/or AI agents. Who we areA healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.Let’s build a healthier future, together.Roche is an Equal Opportunity Employer.

Basel

Senior Engineer - Machine Learning & AI Enablement

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.The PositionAt Roche, we advance science so that we all have more time with the people we love. A healthier future. For a world where everyone has access to the healthcare they need today and for the generations to come. For this, we believe the next breakthrough in medicine will be powered by the intersection of computational engineering and biology. We are building the infrastructure that transforms AI from an experimental concept into a reliable, high-impact utility for our researchers.Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche’s Research and Early Development organizations at Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel computational models to drive impact. The new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness this transformative power of data and AI to assist scientists to deliver more innovative and transformative medicines for patients worldwide.Within the CoE, the Data and Digital Catalyst (DDC) organisation drives the modernization of computational and data ecosystems and integration of digital technologies across Research & Early Development. The AI Enablement Engineering group sits at the heart of this mission. We aren't just training models; we are building scalable systems, data pipelines, and intelligent applications that enable our scientists to work smarter, not harder. From optimizing model performance to designing end-to-end agentic workflows, our goal is to put powerful AI tools directly into the hands of those driving drug discovery to power data-driven science and accelerate decision making.We are a cross-functional, impact-driven team that values cognitive diversity and technical excellence. Here, you’ll partner with biologists, computational scientists, data experts, and researchers to architect a future where AI/ML is an essential component of every scientific discovery. If you’re an engineer who thrives on solving complex problems, spans the stack with curiosity, and wants to build tools that truly change lives, we want to hear from you.The OpportunityAs a Senior Machine Learning Engineer in AI Enablement, you will lead the architecture and delivery of systems that unlock scientific data across complex workstreams. You will own end-to-end technical execution, setting architectural standards that turn AI into a reliable, high-impact utility for researchers.Partnering across computational sciences, product leaders, and engineering teams, you will drive technical strategy and take ownership of critical AI/ML products. You will combine engineering rigor with proactive problem solving to guide cross-functional teams and foster technical growth across the organization.Lead technical design, architecture, and hands-on implementation of agentic AI solutions and scalable data pipelines to solve complex scientific challenges.Drive end-to-end delivery of high-impact products and workstreams, establishing software engineering best practices (testing, CI/CD, documentation) and evaluation standards.Shape foundational architecture decisions, champion best practices through code reviews, and proactively resolve technical bottlenecks.Be willing to span the stack and contribute where needed, even outside of your core area of expertise.Stay up-to-date with emerging technologies and industry best practices and adopt a culture of continuous learning, collaboration, and curiosity.Who You AreYou lead with technical rigor and ownership: You hold a Master’s degree with 5+ years of professional experience or a PhD with 3+ years in Computer Science or a related field, with a track record of driving complex workstreams and establishing architectural best practices.You span the stack: You are comfortable working across the ML lifecycle, from GPU optimization and model performance to backend systems and cloud-native architecture (e.g., Kubernetes, AWS) with solid knowledge of statistics and ML theory as well as AI/ML frameworks, libraries, and toolsetsYou own project delivery and architecture: You excel at delivering AI/ML products, proactively identifying risks, and guiding cross-functional teams (from researchers to DevOps engineers) toward robust, maintainable solutions.You are a continuous learner: You approach new frameworks and languages with curiosity. You are as comfortable mentoring others as you are learning from them, and you actively contribute to a culture of collective growth.You are an excellent communicator: You excel at translating technical complexity into clear, actionable insights for diverse audiences. You communicate with empathy and precision, ensuring that technical trade-offs are well-understood and that all stakeholders, from research scientists to engineers, feel aligned and heard.Experience with biological data (ideally multimodal) and processes is a strong plus.Experience working with scientists or in a research environment is advantageous.Experience with workflow automation, GenAI, and/or agents is a plus. Who we areA healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.Let’s build a healthier future, together.Roche is an Equal Opportunity Employer.

Basel

Sr. Scientist - Computational & Applied AI

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.The PositionAdvances in AI, data, and computational sciences are transforming drug discovery and development. Roche’s Research and Early Development organisations (gRED and pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel computational models to drive impact. Seamless data sharing and access to models across gRED and pRED are essential to maximising these opportunities. The new Computational Sciences Center of Excellence (CS-CoE) is a strategic, unified group whose goal is to harness this transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide.Within this newly established Center of Excellence, our activities operate across a distinct continuum of innovation and explainability. The Computational Biology and Medicine team stands as the vital final link in this continuum. Focussed on our delivery for the portfolio we bridge advanced algorithmic models with deep mechanistic validation to turn AI-driven hypotheses into validated therapeutic targets and deepen our understanding of disease biology and our patients.The OpportunityThe Senior Computational and Applied AI Scientist within the Computational Biology and Medicine team is responsible for developing and deploying translational and applied AI frameworks to accelerate our Immunology and Cardiovascular, Renal, and Metabolism (CVRM) portfolios. Operating at the final stage of translational execution for Discovery and Early Development, you will focus on moving beyond pure statistical correlation toward a systems-level, mechanistic understanding of disease and target biology. This position offers a trajectory of professional development aligned with scientific excellence and modern enterprise productivity frameworks ensuring our computational pipelines directly optimize R&D throughput and compress discovery cycles.Working across departments to co-develop and implement advanced machine learning models focused on explainable and causal AI methods (such as causal models, symbolic regression, and counterfactual inference) to map disease pathways and unlock true mechanistic target validation.Adaptation and fine-tune state-of-the-art biological foundation models to predict novel therapeutic targets in complex immune diseases and CVRM.Bridging the translational gap by implementing adversarial domain adaptation and cross-species translation algorithms to dynamically align animal model phenotypes with human patient endotypes.Leveraging patient-level multi-omics, spatial profiles, and real-world clinical datasets to identify distinct disease endotypes, defining mechanistic patient selection criteria that enable clinical scientists to stratify responder vs. non-responder populations.Constructing dynamic representations and physics-informed models (e.g., Neural ODEs, PINNs) to capture physiological kinetics, temporal disease progression, and patient "digital twins" entirely in silico.Applying graph-based deep learning approaches, building and querying large-scale biological knowledge graphs to capture systems-level interactions across complex tissue-remodeling and auto-inflammatory networks.Anchoring the final stage of the organizational continuum, translating algorithmic innovations and "ML-ready" frameworks directly into high-value portfolio deliverables.Collaborating cross-functionally with clinical scientists, wet-lab disease biology experts, biostatisticians, and enterprise engineers across pRED and gRED to convert ambiguous therapeutic questions into concrete computational pipelines.Ensuring provenance and explainability is an integral feature of your insight delivery to stakeholdersWho you areYou hold a PhD (preferred) or MSc in Computational Biology, Computer Science, Machine Learning, Bioinformatics, Systems Biology, Artificial Intelligence, or a highly quantitative field.You bring 3+ years (Senior Scientist) or 6+ years (Principal Scientist) of post-doctoral or biopharmaceutical industry experience delivering applied AI and data science solutions in a drug-discovery setting.You possess hands-on experience applying causal inference toolkits, graph neural networks, or generative models to high-dimensional biomedical data (single-cell, spatial omics, or clinical trial datasets).You possess experience adapting large-scale biological foundation models or building dynamic systems models to capture temporal disease progression.You demonstrate an active interest or deep domain understanding of human immunology, complex and multifactorial diseases, or system-level pathophysiology.You exhibit elite communication and teamwork skills, with a proven track record of acting as a cross-functional catalyst between pure computational engineers and wet-lab experimentalists.This position is based in Basel, Switzerland Who we areA healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.Let’s build a healthier future, together.Roche is an Equal Opportunity Employer.

Basel

Senior ADS Programmer

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.The PositionSenior ADS ProgrammerA healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche.This role is in Analytical Data Science, a core function within Product Development Data Sciences (PDD) that provides strategic leadership and scientific rigor across Development at Roche. PDD Analytical Data Science teams are mobilized across the portfolio to generate data-driven insights, identify opportunities for scale, and implement impactful solutions.PDD Analytical Data Science is recognized as a leading hub for top industry talent, operating as an agile workforce to deliver regulatory commitments across the portfolio. We identify, influence, and adopt industry-leading digital and automation solutions, develop analytical approaches to support exploratory analyses, and align statistical programming practices across both early- and late-stage clinical development. The Opportunity:The Analytical Data Science Programmer is a key contributor to the clinical study team, responsible for transforming statistical analysis plans into high-quality, traceable programming deliverables. This includes both static and dynamic outputs, such as tables, listings, figures, and interactive data visualizations or dashboards. The role involves creating and validating datasets in accordance with Study Data Tabulation Model and Analysis Data Model standards, ensuring compliance with regulatory requirements and Roche standards. In addition to supporting regulatory submissions, the ADS Programmer plays a critical role in generating data insights through platforms such as the Insight Engine, enabling real-time exploration and interpretation of diverse clinical and exploratory data. This role contributes to a modern, insight-driven development environment by facilitating robust, timely, and decision-enabling analytics across clinical programs.You independently develop, validate, and maintain datasets and statistical outputs for clinical trials, including Study Data Tabulation Model (SDTM) datasets, Analysis Data Model (ADaM) datasets, and tables, listings, and figures (TLFs), ensuring programming accuracy, traceability, and compliance with internal processes and regulatory expectationsYou develop and support programming outputs across a wide range of data types, including exploratory biomarker data and real-world data, to support both regulatory and scientific objectivesYou collaborate on exploratory analyses that span disease areas and therapeutic areas, enabling insight generation to inform drug development strategiesYou support the creation and refinement of interactive tools and analytical applications (e.g., dashboards or visual data platforms) that enable dynamic exploration of integrated datasets by scientific and clinical teamsYou provide programming leadership for assigned studies, coordinating deliverables across internal and external programming partners to meet study timelines and requirementsYou interpret statistical analysis plans and translate them into executable programming specifications to ensure scientific rigor in outputsYou troubleshoot and resolve technical programming challenges with limited supervision, proactively identifying risks and implementing effective solutions while meeting timelinesYou contribute to the design and maintenance of standard macros and reusable components, promoting efficiency and consistency across multiple studies and projectsYou document programming workflows and maintain audit trails, ensuring study files are complete, traceable, and inspection-readyYou work cross-functionally with stakeholders, including biostatistics, data management, and clinical operations, to define programming timelines and deliverablesYou engage in process improvement and innovation activities and participate in learning activities to grow knowledge of clinical research and programming standardsWho you are:You hold a Bachelor’s or Master’s degree in Statistics, Computer Science, Mathematics, Life Sciences, or a related fieldYou have a minimum of 5 years of experience in statistical programming in a clinical development setting, or an advanced degree with 3 years of equivalent work experienceYou are proficient in or have working knowledge of a modern programming language (such as SAS or R) and visualization/review toolsYou have a deep understanding of statistical quality, endpoints, and QC processesYou have experience with Clinical Data Interchange Standards Consortium (CDISC) standards (e.g., SDTM and ADaM)You bring expertise in handling and analyzing different types of data (multi-modal)You have demonstrated ability to deliver programming outputs independentlyYou demonstrate respect for cultural differences when interacting with colleagues in the global workplaceYou are fluent in EnglishPreferred:Possess attention to detail for regulatory submission processes and related documentationDemonstrate critical thinking, strong organizational and problem-solving skillsExperience working in cross-functional global study teamsEffective communication skills with the ability to translate complex statistical concepts for non-statistical audiencesExperience with multiple phases of drug development (early and/or late stage)Excellent communication skills, including the ability to influence and translate complex data for non-technical stakeholdersDemonstrated willingness to adapt, grow, and evolve in response to shifting prioritiesLocationThis position is based in BaselRelocation Assistance is not available Who we areA healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.Let’s build a healthier future, together.Roche is an Equal Opportunity Employer.

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