Software Engineering jobs in Basel

Principal / Senior Principal Software Engineer

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections,  where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.The PositionA healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche.Advances in AI, data and computational sciences are transforming drug discovery and development. Roche’s Research and Early Development organizations at Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel computational models to drive impact. Seamless data sharing and access to models across gRED and pRED are essential to maximising these opportunities. The Computational Sciences Center of Excellence (CS CoE) is a strategic, unified group whose goal is to harness the transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and life-changing  medicines for patients worldwide.Within the CS CoE organisation, the Data and Digital Catalyst (DDC) organization leads the modernization of our computational and data ecosystems by integrating digital technologies across Research and Early Development to empower stakeholders, advance data-driven science and accelerate decision-making.The Solutions team within the DDC Organization develops modernized and interconnected computational and data ecosystems. The Data Ecosystem is foundational to building solutions that accelerate the work done by our Computational and Bench Scientists and enable ML/AI tool creation and adoption. Our team specializes in building Data Pipelines and Applications for data acquisition, collection, storage, transformation, linkage and sharing. Join our Data and Digital Catalyst team as a Software Engineer, where you will develop the modernized and interconnected computational and data ecosystems that are foundational to our research. You'll build robust and scalable systems that unlock the potential of our diverse scientific data, directly accelerating the discovery and development of life-changing treatments for patients. This is a unique opportunity to empower our scientists and advance data-driven science through innovative technology.The OpportunityDesign and build interactive tools for both small and large molecule drug discovery integrating data, molecular design workflows, computational algorithms, and AI models.Build and enhance a modern, scalable ecosystem of applications and tools to capture, move, and prepare scientific data for analysis.Design and deliver complex, user-friendly data applications and pipelines that integrate diverse data sets across key scientific domains.Leverage standard patterns like microservices and event-driven architecture to improve our data workflows and application ecosystem.Champion technical excellence by ensuring our solutions are innovative, best-in-class, and seamlessly integrated.Integrate diverse data sets to power Artificial Intelligence (AI), machine learning (ML), and Natural Language Search capabilities.Collaborate directly with computational and research scientists to understand their challenges and translate them into effective technology solutions.Provide technical leadership on ongoing initiatives and identify new opportunities to build common, reusable solutions.Mentor junior developers, fostering their professional growth and upholding high engineering standards.Who You AreWe are looking for a passionate and collaborative software engineer with experience building scalable platforms for drug discovery or a related domain. You thrive on engaging with scientific partners to solve complex challenges and are dedicated to engineering best practices.A Ph. D. or equivalent experience of 8-10+ years working in life science domain building full-stack software solutions, preferably for drug discovery and strong software engineering expertise in all layers of stack including backend (e.g., Python, Java) and frontend (e.g., React, Vue) is required.Deep experience with modern data engineering, including databases (SQL/NoSQL), data engineering (ETL/ELT), and APIs (REST, GraphQL)Proven experience developing and deploying applications on cloud-native architectures, preferably AWS and experience in setting up SDLC best practices for the team including versioning, testing, observability, CI/CD, etc. Exceptional abilities to architect scalable solutions in complex environment with multiple existing system integrations and demonstrated proficiency in applying AI-assisted and agentic coding practices, both as an individual contributor and collaboratively within a team environment.Outstanding communication and collaboration skills, with the ability to articulate technical concepts to diverse audiences.Preferably experience working in pharmaceutical or a related domain and in setting best-practices for agentic coding producing maintainable code.The Global Grade for this role can be: SE7 or SE8 to align with Principal / Sr. Principal Engineer#ComputationCoE#tech4lifeComputationalSciences       Who we areA healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.Let’s build a healthier future, together.Roche is an Equal Opportunity Employer.

Biocatalysis and Protein Engineering - Industrial Post Doctoral Researcher in Global Discovery Chemistry (Novartis Genesis Labs)

Salary Range:CHF0.00 - CHF0.00 Job Description Summary18. That's the number of months you will spend embedded in Global Discovery Chemistry (GDC) as an Industrial Postdoc, working at the heart of Novartis's most ambitious internal innovation initiative — the Genesis program. We are looking for a highly motivated, bold-thinking postgraduate scientist with expertise in biocatalysis, protein engineering, synthetic biology or a closely related field, ready to develop transformative technology platforms that reshape how medicines are discovered and made.This is not a conventional postdoc. Genesis is Novartis's flagship internal innovation program — structured as an internal startup within one of the world's leading pharmaceutical companies. Think of it as the intellectual challenge and pace of an early-stage biotech, backed by the resources, scientific depth, and pipeline of Novartis Biomedical Research. We will encourage you to move fast, think big, and work on problems that matter — with the support of a world-class interdisciplinary team around you.This role is a unique opportunity to work at the cutting edge of applied biocatalysis and protein engineering, at the interface between research and development, with direct impact on the Novartis portfolio. You will not only transfer your scientific knowledge into practice — you will develop your leadership skills, build a powerful internal and external network, and lay the foundation for an exceptional career in the pharmaceutical industry or academia. Job DescriptionYour ResponsibilitiesYour responsibilities include, but are not limited to:Design and develop innovative technology platforms in biocatalysis and protein engineering as part of the Genesis flagship program, advancing Novartis's discovery capabilities at speed.Conduct enzyme discovery and engineering campaigns — leveraging latest computational tools and high-throughput automated screening — to identify and optimise novel biocatalysts for pharmaceutical synthesis applications.Develop novel biocatalytic synthetic solutions that enable efficient, scalable, and sustainable preparation of drug candidates across novel modalities, from early discovery through to clinical and commercial supply.Get exposure to peptide chemistry and display technologies to expand the scope and diversity of biocatalytic solutions available to the Novartis portfolio.Apply cutting-edge automation platforms and advanced automation for high-throughput enzyme screening, data-rich experimentation, and rapid iteration across engineering campaigns.Contribute to defining scientific strategy on Genesis program projects — identifying bold opportunities, designing novel experimental approaches, and helping shape the direction of the platform.Collaborate with world-class experts in Molecular Biology, Biochemistry, Bioinformatics, Process Chemistry, Chemical Engineering, and Analytical Chemistry across Novartis and with external academic and industry partners.Communicate your science — present findings internally, contribute to patents, and make complex science accessible to diverse audiences.What You'll Bring to the RoleA completed PhD at the interface of Chemistry and Biology with a focus on biocatalysis, synthetic biology, enzyme engineering, or a closely related discipline.Hands on experience in development of  peptide-, or protein-modifying enzymatic transformations is preferred.Strong track record of original research and the ability to develop innovative (bio)catalytic transformations.Scientific curiosity and team spirit to effectively work at the interface of multiple scientific disciplines in a fast-paced, multicultural environment.Effective interpersonal and communication skills are essential.Effective knowledge of English, both oral and written, is required.Experience with state-of-the-art high throughput, computation or display technologies as well as previous post-doctoral experience is a further advantage but not a requirement.Why Consider Novartis?750 million. That's how many lives our products touch. And while we're proud of that, in this world of digital and technological transformation, we must also ask ourselves: how can we continue to improve and extend even more people's lives?We believe the answers are found when curious, courageous, and collaborative people like you are empowered to ask new questions, make bolder decisions, and take smarter risks.At Novartis Biomedical Research, you will have access to state-of-the-art infrastructure — advanced automation, high-throughput screening, computational design platforms, and structural biology capabilities. You will be mentored by world-class scientists and embedded in a scientific community that spans academic leaders, industry partners, and the Novartis global network. You will publish, present, and file patents. And through the Genesis program, you will experience something that is genuinely rare in large-company R&D: the energy, pace, and creative latitude of a startup, combined with the resources and pipeline of a top-five global pharmaceutical company. Skills Desired

Student Internship in Device Development and Verification Engineering (Basel, 9-12 months)

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections,  where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.The PositionThe global Device Development unit at F. Hoffmann-La Roche is responsible for the development of medical devices, combination products for R&D portfolio drug products. The department’s activities comprise a wide range of engineering disciplines ranging from the initial definition of product requirements to first commercialization and subsequent product care considering required regulatory, legislative, ecological, economical and technical aspects.Within the department, the Section Verification Engineering is responsible for the generation and management of experimental and cGMP verification activities providing objective evidence that the medical device/combination products perform according to patient`s and technical expectations. Thereby, Verification Engineering supports the evaluation, selection, design, development, characterization, and industrialization of medical devices, combination products and packaging systems (e.g., pre-filled syringe, needle safety device, autoinjector, infusion pump, blisters, bottles, new & break-through & platform technology, special packaging).The OpportunityAs an intern, you will be part of the Verification Engineering Section. During your internship you will be assigned to mentors, to research and coordinate a significant project including:technical assessment and implementation of new equipmentassess parameters impacting primary packaging/device functionality perform tests including statistical evaluation to assess method comparability / capabilities (proof-of-concept study, Design of Experiment)develop test methods summary and presentation of resultssupport practical testing for related projectsWho You AreYou are an enrolled Bachelor's or Master's student, or you have received your degree within the last 12 months, pursuing a qualification in pharmaceutical sciences, physics, chemistry, engineering, materials science or a comparable subject.  You are someone who wants to influence your own development, and you are looking for a company providing the opportunity to pursue your interests across functions and geographies - where a job title is not the final definition of who you are, but the starting point. Furthermore, you have:already gained first experience with measurement systems and their application in the development of medical devices, combination products or packaging systemsfluent spoken and written English knowledge excellent documentation, presentation and interpersonal skills good user skills in standard office IT packagesAdditional preferred skills include:demonstrable practical knowledge of laboratory hands-on work and developing test methods for a given applicationexperience of working in pharma or other closely-regulated environment experience with numerical simulations of physical processesgood knowledge of statistical techniques and scientific writing German knowledge is of advantageApplication processPreferred start date: 1. February 2027Duration: 9 - 12 monthsPlease apply with a valid certificate of enrollment or degree certificate, a cover letter and a CV.Non EU/EFTA citizens are required to upload a certificate of mandatory internship in addition.Ready for the next step? We look forward to hearing from you. Apply now to discover this exciting opportunity!  Who we areA healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.Let’s build a healthier future, together.Roche is an Equal Opportunity Employer.

Advanced Manufacturing Technology Lead

Today, Lonza is a global leader in life sciences operating across five continents. While we work in science, there’s no magic formula to how we do it. Our greatest scientific solution is talented people working together, devising ideas that help businesses to help people. In exchange, we let our people own their careers. Their ideas, big and small, genuinely improve the world. And that’s the kind of work we want to be part of.We are looking for Senior Director, Advanced Manufacturing Technology Lead to join our team!The Advanced Manufacturing Technology Lead defines and advances the cross-platform manufacturing technology agenda across Integrated Biologics, Advanced Synthesis and Specialized Modalities. The role identifies, evaluates and matures technologies that can materially improve productivity, autonomy, process control, quality assurance, flexibility and unit cost across manufacturing operations.The role focuses on reusable manufacturing technologies such as robotics, automation, automated material movement, smart sensing, PAT, process monitoring, process prediction, advanced control, digital twins and operator support technologies.The Advanced Manufacturing Technology Lead works closely with the Factory of the Future, Lab of the Future and Data Strategy & Products Leads to ensure technology solutions support the required manufacturing concepts, analytical capabilities and data needs, and can be scaled across platforms, sites and future builds. Key responsabilities:Technology Strategy & Roadmap• Define the cross-platform advanced manufacturing technology roadmap• Identify opportunities in robotics, automation, material movement, sensing, PAT, prediction and advanced process control• Assess technology maturity, applicability and scalability• Translate emerging technologies into prioritized manufacturing use casesLighthouse & Solution Development• Identify and prioritize cross-platform lighthouse opportunities• Drive technology assessment, partner selection and solution concept development• Ensure lighthouse solutions address clear operational or quality needs• Define success criteria and replication potentialIntegration with Manufacturing, Lab & Data• Translate manufacturing requirements into relevant technology solutions• Align sensing, monitoring and quality-related technologies with Lab of the Future• Align data and analytics requirements with Data Strategy & Products• Ensure solutions are integrated into coherent manufacturing conceptsScale-up & Replication• Convert proven solutions into reusable deployment requirements• Identify replication opportunities across platforms, sites and future builds• Support standardization of successful technologies and interfaces• Feed technology learnings into future manufacturing concepts and investment decisions Key requirements:• Bachelor or Master in Engineering, Automation, Robotics, Computer Science, or a related discipline• Highly Experienced in Advanced Manufacturing Technology, Automation & Operations Transformation• Highly Experienced in Development & Industrial Scale-Up• Ability to define cross-platform roadmaps across robotics, automation, material movement, sensing, PAT, prediction, advanced control, digital twins and operator-support technologies• Strong understanding of biopharmaceutical manufacturing, automation architectures, process monitoring and control, equipment interfaces and GMP requirements• Ability to quantify productivity, autonomy, quality, flexibility and unit-cost potential and translate it into prioritized use cases and investment cases• Ability to integrate equipment, automation, sensing, data, analytics and operator workflows into maintainable solutions with reusable interfaces• Demonstrated ability to lead multidisciplinary solution teams, assess suppliers and research partners, and drive concept development without relying on direct authority• Ability to communicate technology maturity, risks, architecture choices, evidence and recommendations clearly to technical, operational and executive stakeholders• Experience assessing readiness, technical and compliance risks, success criteria and dependencies and using evidence to support go, adapt or stop decisions• Ability to convert proven lighthouse solutions into reusable technical requirements, standards, interfaces and deployment recommendations across platforms, sites and future buildsEvery day, Lonza’s products and services have a positive impact on millions of people. For us, this is not only a great privilege, but also a great responsibility. How we achieve our business results is just as important as the achievements themselves. At Lonza, we respect and protect our people and our environment. Any success we achieve is no success at all if not achieved ethically.People come to Lonza for the challenge and creativity of solving complex problems and developing new ideas in life sciences. In return, we offer the satisfaction that comes with improving lives all around the world. The satisfaction that comes with making a meaningful difference.

Senior ADS Programmer

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections,  where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.The PositionSenior ADS ProgrammerA healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche.This role is in Analytical Data Science, a core function within Product Development Data Sciences (PDD) that provides strategic leadership and scientific rigor across Development at Roche. PDD Analytical Data Science teams are mobilized across the portfolio to generate data-driven insights, identify opportunities for scale, and implement impactful solutions.PDD Analytical Data Science is recognized as a leading hub for top industry talent, operating as an agile workforce to deliver regulatory commitments across the portfolio. We identify, influence, and adopt industry-leading digital and automation solutions, develop analytical approaches to support exploratory analyses, and align statistical programming practices across both early- and late-stage clinical development. The Opportunity:The Analytical Data Science Programmer is a key contributor to the clinical study team, responsible for transforming statistical analysis plans into high-quality, traceable programming deliverables. This includes both static and dynamic outputs, such as tables, listings, figures, and interactive data visualizations or dashboards. The role involves creating and validating datasets in accordance with Study Data Tabulation Model and Analysis Data Model standards, ensuring compliance with regulatory requirements and Roche standards. In addition to supporting regulatory submissions, the ADS Programmer plays a critical role in generating data insights through platforms such as the Insight Engine, enabling real-time exploration and interpretation of diverse clinical and exploratory data. This role contributes to a modern, insight-driven development environment by facilitating robust, timely, and decision-enabling analytics across clinical programs.You independently develop, validate, and maintain datasets and statistical outputs for clinical trials, including Study Data Tabulation Model (SDTM) datasets, Analysis Data Model (ADaM) datasets, and tables, listings, and figures (TLFs), ensuring programming accuracy, traceability, and compliance with internal processes and regulatory expectationsYou develop and support programming outputs across a wide range of data types, including exploratory biomarker data and real-world data, to support both regulatory and scientific objectivesYou collaborate on exploratory analyses that span disease areas and therapeutic areas, enabling insight generation to inform drug development strategiesYou support the creation and refinement of interactive tools and analytical applications (e.g., dashboards or visual data platforms) that enable dynamic exploration of integrated datasets by scientific and clinical teamsYou provide programming leadership for assigned studies, coordinating deliverables across internal and external programming partners to meet study timelines and requirementsYou interpret statistical analysis plans and translate them into executable programming specifications to ensure scientific rigor in outputsYou troubleshoot and resolve technical programming challenges with limited supervision, proactively identifying risks and implementing effective solutions while meeting timelinesYou contribute to the design and maintenance of standard macros and reusable components, promoting efficiency and consistency across multiple studies and projectsYou document programming workflows and maintain audit trails, ensuring study files are complete, traceable, and inspection-readyYou work cross-functionally with stakeholders, including biostatistics, data management, and clinical operations, to define programming timelines and deliverablesYou engage in process improvement and innovation activities and participate in learning activities to grow knowledge of clinical research and programming standardsWho you are:You hold a Bachelor’s or Master’s degree in Statistics, Computer Science, Mathematics, Life Sciences, or a related fieldYou have a minimum of 5 years of experience in statistical programming in a clinical development setting, or an advanced degree with 3 years of equivalent work experienceYou are proficient in or have working knowledge of a modern programming language (such as SAS or R) and visualization/review toolsYou have a deep understanding of statistical quality, endpoints, and QC processesYou have experience with Clinical Data Interchange Standards Consortium (CDISC) standards (e.g., SDTM and ADaM)You bring expertise in handling and analyzing different types of data (multi-modal)You have demonstrated ability to deliver programming outputs independentlyYou demonstrate respect for cultural differences when interacting with colleagues in the global workplaceYou are fluent in EnglishPreferred:Possess attention to detail for regulatory submission processes and related documentationDemonstrate critical thinking, strong organizational and problem-solving skillsExperience working in cross-functional global study teamsEffective communication skills with the ability to translate complex statistical concepts for non-statistical audiencesExperience with multiple phases of drug development (early and/or late stage)Excellent communication skills, including the ability to influence and translate complex data for non-technical stakeholdersDemonstrated willingness to adapt, grow, and evolve in response to shifting prioritiesLocationThis position is based in BaselRelocation Assistance is not available  Who we areA healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.Let’s build a healthier future, together.Roche is an Equal Opportunity Employer.